Anaferon, released-active from of antibodies to IFNγ, as an effective medicine for treatment and prophylaxis of a wide spectrum of infections

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چکیده

Anaferon, released-active from of antibodies to interferon-gamma, is an antiviral drug with immunomodulating activity. The long-term experience proved its efficacy and safety in the treatment and prophylaxis of a wide spectrum of viral and bacterial infections. The key mechanisms of anaferon action are the regulation of endogenous interferons, in particular interferon-gamma: induction conformational changes in interferon-gamma regions that play essential roles in interferongamma specific binding to its receptor, resulting in activation of the interferon-gamma signaling pathway and antiviral activity. Excellent safety profile, possibility of its combination with other medicines, absence of withdrawal have made it a drug of choice for the treatment and prophylaxis of various infections. Correspondence to: Gorbunov EA, 47-1, Trifonovskaya Street, 129272 Moscow, Russian Federation, Tel: +7 495 276 1571, ext. 119; Fax: +7 495 276 1571, ext. 001; E-mail: [email protected]

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تاریخ انتشار 2016